Ana’s paper describing the structure of a slightly cryptic domain from CHD4 has come out in JBC. Check out the paper here or check out the structure here. As you can see here, it looks sort of like an HMG-box domain (CHD4 is in red – HMG-box domains are in grey). HMG-box domains bind to DNA – sometimes to unusual structures… Seems like it might be involved in binding to PAR at sites of DNA damage, although that’s not set in stone at this stage…
Jakob Helmbrecht bravely ventured down under, risking crocodile attacks and leech bites to work...
Michael, a BSc Hons student in the lab in 2012, now has an independent group leader position at...
We ventured out into the lower Blue Mountains for a day hike on Sat 24 Feb. The forecast was...
We recently had a camera crew in the lab from Horticultural Innovation Australia. They are...
Several lab members took the opportunity to attend the annual meeting of the NSW chapter of the...
At the recent ASBMB annual meeting in Canberra (which was an excellent meeting, I thought -...