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New PNAS Paper for Neil, Ngaio, and Athina!

Two papers in two days! Neil, Ngaio, and Athina just had some very exciting binding findings published in PNAS! This work includes Neil’s crazy binding kinetics equations, some gorgeous EMSA data from Ngaio, and other data from Athina, Matt, and Ann. The paper shows that a single disordered region can interact with other structured domains using different binding mechanisms dependent on the structured partner. With heavy implications for protein complex formation during development, this work was wide in scope and is leading to interesting follow-up work in the lab. Congratulations to all on this fantastic accomplishment! Drinks all around!