Fionna’s new protein-RNA complex structure appears in Molecular Cell

Lab alumna Fionna Loughlin – now working at Monash – has published the culmination of several years of her postdoctoral work in Fred Allain’s lab at ETH in Zurich just last week in Molecular Cell [here]. She has determined the structures of several domains of the protein FUS bound to RNA sequences, and shown how they contribute to FUS-mediated splicing. FUS biology/biochemistry is a hot topic these days – given it’s ability to form phase-separated structures – so it’s good timing. Top effort pushing this through, Fionna!