Data Hall of Fame

Super-duper HSQC titration data

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Karishma has been busily recording HSQC spectra for a whole set of protein-peptide interactions we’re looking at (let’s see – there are 18 peptides and 6 proteins – so she has about 108 titrations to do if we go the whole hog). So far, a decent proportion of them have been exceptionally good – like […]

Data Hall of Fame

GATA1-DNA structure published

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The long-awaited structure of the double ZF of GATA1 bound to DNA – a pseudopalindromic site – has come out [Pubmed or PDF via journal] in Protein Science, thanks to the work of Lorna (including some *very* funky multi-coloured gel shifts), Krystal and Nina – and of course the inimitable David Jacques and Mitchell. Their […]

Data Hall of Fame

A blast from the past…

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Look what turned up in a lab cleanup a little while ago. What is the probability of finding a gel that has lanes on it from both Jacqui *and* Joel being at the bench at the same time?!?! See it with your own eyes! I would note that the lanes with the best expression were […]

Data Hall of Fame

Molecule of the Month!

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One of our most prized structures, the GATA:FOG zinc finger complex, features in the Protein Data Bank’s Molecule of the Month section for March 2007. Check it out! A couple of our recent reviews of the field (Sunde and Matthews and Gamsjaeger et al.) were also used to create the feature.