Michael Webster wins EMBO Fellowship

Michael, who has just recently finished his PhD at the LMB in Cambridge with Lori Passmore, has been successful in winning an EMBO postdoctoral fellowship to fund his work in Albert Weixlbaumer’s lab in Strasbourg. Here, he will investigate how translation is linked to transcription in bacteria, by assembling complexes of ribosomes and RNA polymerases and characterizing their structure by cryo-EM and their activity with biochemical assays. A fantastic opportunity – and a great place for us to visit if we happen to be in that part of the world – well done Michael!

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Update from Antonia

Antonia Zech – who worked with Ana for 5 months in 2013-4 as part of her Masters degree in Hamburg – has sent us an update on her activities. She has been doing a PhD at the Institute of Experimental Pharmacology and Toxicology at the University Medical Center Hamburg-Eppendorf – in the group of Lucie Carrier. She is working on understanding the process of autophagy in hypertrophic cardiomyopathy, using techniques like confocal microscopy, gene therapy and working with iPS-cells. More importantly though, she has also been busy creating a family. Emil Isaac was born (a little while ago – on …

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Xavier gets to put the gown on

Xavier Reid graduated today with his BSc with first class Honours – and you can see him here accompanied by his co-supervisor, Dr Jason Low. No one will mention that Jason isn’t wearing his UNSW gown… Xavier has taken the plunge to come back and start a PhD – splitting his time between digging deep into NuRD complex biochemistry and designing new high-affinity, high-specificity regulators of gene expression, using the new RaPID screening technology that has landed at USyd with the arrival of Dr Toby Passioura.

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Mehdi and Jason’s paper accepted at FEBS J

In exciting news, we have had our paper “The stoichiometry and interactome of the Nucleosome Remodelling and Deacetylase (NuRD) complex are conserved across multiple cell lines” accepted in FEBS J [epub here]. It’s particularly exciting both because it’s Mehdi’s first first-author paper from his PhD and it is also Jason’s first last- and corresponding-author paper. Congratulate them if you see them… The stoichiometry and interactome of the Nucleosome Remodeling and Deacetylase (NuRD) complex is conserved across multiple cell lines

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A nice piece of work from Nina

Nina Ripin, who spent some months in the lab as a Masters’ student in 2011, is the lead author on a nice study focused on the RNA-binding properties of HuR in the latest PNAS. She has combined NMR and X-ray crystallography while working in Fred Allain’s lab at ETH in Zurich to characterize the means by which this protein uses its RRM domains to bind to AU-rich RNA elements. You can read it here.

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