Papers

Our Peppy VR paper hits the airwaves!

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Our great collaboration with David Doak, Jane Allison, Juliet Gerrard and Gareth Denyer is now out in Protein Science here . Peppy VR is a Unity application written by David (of Goldeneye fame), advised on by Juliet, Jane and myself and tested in real-life teaching classes by Gareth. You can get it free here for […]

Papers

New lab paper hits the streets

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Well, this paper took quite some time to come to fruition. Biswa from Melbourne worked hard to extract a structure from some less than friendly NMR data on a protein that was gifted to us by Wayne Patrick (formerly in Otago, now in Victoria University Wellington). I’m not sure it’s a gift I’d wish on […]

Lab Members

Mehdi and Jason’s paper accepted at FEBS J

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In exciting news, we have had our paper “The stoichiometry and interactome of the Nucleosome Remodelling and Deacetylase (NuRD) complex are conserved across multiple cell lines” accepted in FEBS J [epub here]. It’s particularly exciting both because it’s Mehdi’s first first-author paper from his PhD and it is also Jason’s first last- and corresponding-author paper. […]

Lab Members

A nice piece of work from Nina

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Nina Ripin, who spent some months in the lab as a Masters’ student in 2011, is the lead author on a nice study focused on the RNA-binding properties of HuR in the latest PNAS. She has combined NMR and X-ray crystallography while working in Fred Allain’s lab at ETH in Zurich to characterize the means […]

Lab Members

Marylène has been extra busy…

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Not only has she been planning a wedding, but she’s been publishing senior author papers too. Here is her paper in J Mol Biol describing the combinatorial design of a nanobody that can recognized structured RNA molecules: Marylène’s paper! A nice piece of work – well done Marylène – it’s tough work getting them nailed down in […]

Lab Members

New PNAS Paper for Neil, Ngaio, and Athina!

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Two papers in two days! Neil, Ngaio, and Athina just had some very exciting binding findings published in PNAS! This work includes Neil’s crazy binding kinetics equations, some gorgeous EMSA data from Ngaio, and other data from Athina, Matt, and Ann. The paper shows that a single disordered region can interact with other structured domains […]

Lab Members

New JBC Paper for Dorothy and Taylor!

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Hot off the presses! Dorothy and Taylor’s new ET paper just came out in JBC! This work features two solution NMR structures of the ET domain of Brd3 bound to peptides from chromatin remodelling proteins CHD4 and Brg1. This work also includes SPR data from Lorna and pulldowns from Jason and Cherry with other contributions […]

Papers

Paper featured in special edition of JBC!

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JBC is putting out a special virtual issue with a focus on protein science in Australasia to honour the Lorne Protein conference and we received word that one of our papers is featured! “CHD4 Is a Peripheral Component of the Nucleosome Remodeling and Deacetylase Complex” is a collaborative effort with Nick Shepherd involving Jason, Ana, […]

Papers

New lab paper accepted FEBS J

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Mario’s long journey to publish the carefully methodical work he and others have done on the inter-subunit interaction network within the NuRD complex has finally come to fruition as his paper is now accepted in FEBS J. We’re quite fond of the paper because it makes a statement about the uncertain nature of pulldown experiments […]