Lab Members

New JBC Paper for Dorothy and Taylor!

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Hot off the presses! Dorothy and Taylor’s new ET paper just came out in JBC! This work features two solution NMR structures of the ET domain of Brd3 bound to peptides from chromatin remodelling proteins CHD4 and Brg1. This work also includes SPR data from Lorna and pulldowns from Jason and Cherry with other contributions […]

Papers

Paper featured in special edition of JBC!

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JBC is putting out a special virtual issue with a focus on protein science in Australasia to honour the Lorne Protein conference and we received word that one of our papers is featured! “CHD4 Is a Peripheral Component of the Nucleosome Remodeling and Deacetylase Complex” is a collaborative effort with Nick Shepherd involving Jason, Ana, […]

Papers

New lab paper accepted FEBS J

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Mario’s long journey to publish the carefully methodical work he and others have done on the inter-subunit interaction network within the NuRD complex has finally come to fruition as his paper is now accepted in FEBS J. We’re quite fond of the paper because it makes a statement about the uncertain nature of pulldown experiments […]

Papers

Morgan’s latest paper from chilly Dundee

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Morgan Gadd, ex-PhD student of Jacqui’s, has just published a paper from his postdoc time with Alessio Cuilli – a nice piece of work where they examine one of their bi-functional bromodomain inhibitors and show that it forms a tight ternary complex with their small molecule and the other protein that it brings along with […]

Papers

Dorothy’s paper accepted at NAR

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Dorothy has had a pretty painless first foray into the world of publishing papers with her paper on the RNA-binding properties of the transcription factor YY1 being accepted at Nucleic Acids Research. We were very pleased with the outcome given that we weren’t trumpeting sequence-specific binding with high affinity, but rather low specificity and moderate […]

Papers

Our latest CHD4 work makes it into JBC

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Well, this one wasn’t *quite* as straightforward as the Protein Science paper I mentioned recently, but in the end the reviewers *did* actually improve the paper I think. You can read about the efforts of Jason (L), Sarah, Ana, Hinnerk, Mario, Mattias and Nick – with able assistance from Daniel in Canberra and Ben Parker […]

Papers

Our first EM data published in Protein Science

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Whew! It was quite a roller coaster ride to this paper. After seeing an abstract by John Schwabe’s group in Leicester that covered work very similar to what we’ve been hammering away at for a while, we scrambled to get a paper prepared and submitted. During the process, I contacted a number of journals and […]