Papers

Fionna publishes a nice paper!

Posted on

Fionna has just had her first paper published from her postdoc with Fred Allain at the ETH in Zurich – in NSMB, no less! While simultaneously juggling a small child (not literally) she has published her structure of the zinc knuckle domains of Lin28 (an inhibitor of miRNA biosytnthesis) bound to a pre-miRNA from Let7 […]

Papers

If you are looking for a good read…

Posted on

…then look no further than the latest blockbuster from Mackay and Segal. Packed with juicy material on the bipartite selection of zinc fingers by phage display, the lowdown on inhibition of viral transcription by zinc finger proteins and the shocking tale of transgenic mice expressing an artificial zinc finger protein that targets an endogenous gene, […]

Papers

Liza publishes in Nature!

Posted on

After a long reviewing process, Dr Liza Cubeddu, a National Breast Cancer Foundation Fellow in Jacqui’s lab, has just seen some of her work finally appear in Nature (PubMed). This paper describes a new human single-stranded DNA binding protein that is essential for genomic stability – the work originated from Liza’s previous life in St […]

Data Hall of Fame

Molecule of the Month!

Posted on

One of our most prized structures, the GATA:FOG zinc finger complex, features in the Protein Data Bank’s Molecule of the Month section for March 2007. Check it out! A couple of our recent reviews of the field (Sunde and Matthews and Gamsjaeger et al.) were also used to create the feature.

Papers

Cover Story

Posted on

Our most recent paper, a collaboration with Peter Karuso, on the solution properties of DNA-binding ruthenium complexes, made the cover of Dalton Transactions, a Royal Society of Chemistry journal.