Papers

If you are looking for a good read…

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…then look no further than the latest blockbuster from Mackay and Segal. Packed with juicy material on the bipartite selection of zinc fingers by phage display, the lowdown on inhibition of viral transcription by zinc finger proteins and the shocking tale of transgenic mice expressing an artificial zinc finger protein that targets an endogenous gene, […]

Papers

Liza publishes in Nature!

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After a long reviewing process, Dr Liza Cubeddu, a National Breast Cancer Foundation Fellow in Jacqui’s lab, has just seen some of her work finally appear in Nature (PubMed). This paper describes a new human single-stranded DNA binding protein that is essential for genomic stability – the work originated from Liza’s previous life in St […]

Data Hall of Fame

Molecule of the Month!

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One of our most prized structures, the GATA:FOG zinc finger complex, features in the Protein Data Bank’s Molecule of the Month section for March 2007. Check it out! A couple of our recent reviews of the field (Sunde and Matthews and Gamsjaeger et al.) were also used to create the feature.

Papers

Cover Story

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Our most recent paper, a collaboration with Peter Karuso, on the solution properties of DNA-binding ruthenium complexes, made the cover of Dalton Transactions, a Royal Society of Chemistry journal.