by Joel Mackay | Oct 13, 2020 | BLOG |
A big paper for us – out now here! Working with Louise Walport and Toby Passioura, who were themselves working with Hiroaki Suga at the University of Tokyo at the time, we have used Suga’s RaPID version of mRNA display to discover cyclic peptide inhibitors...
by Joel Mackay | Jul 31, 2020 | BLOG |
This week’s edition of Science magazine features an article on which Kaavya Krishna Kumar – PhD student with Dave Gell when he was here in our unit – is first-equal author. The paper describes the cryoEM structure of the glucagon receptor bound to a...
by Joel Mackay | Feb 19, 2020 | BLOG |
We have posted our analysis of NuRD complex architecture on Biorxiv. We firm up the stoichiometry, show that there is large-scale dynamics, partially map architecture using XLMS and show direct competition by PWWP2A that steals half the complex! It’s been a...
by Joel Mackay | Dec 4, 2019 | BLOG |
Molecular Microbiology has now published the epic piece of work spearheaded by ex-lab member Dave Gell, who is now resident at the University of Tasmania. Dave had been approached by local microbiologists who noted that some strains of Haemophilus haemolyticus...
by Joel Mackay | Nov 24, 2019 | BLOG |
The project that Karishma has been hammering away at for the last couple of years – with substantial input from collaborators Louise Walport (Crick Institute, London) and Toby Passioura (now USyd) – has been somehow condensed into a manuscript and posted...