After about 7 years of painstaking work (!), we have finally been able to solve and publish the structure of the complex formed between the N-terminal zinc finger of GATA-1 and a classical finger from FOG. This work was made very difficult by the weak nature of the complex (~104-105 M-1), which presented line-broadening problems.
Finally though, we got there and were able to report the structure in PNAS (Track II) – a great relief for all involved! Now to bring in other members of these complexes…
It’s good to see that when I go away, the lab is still productive!
It’s good to see that when I go away, the lab is still productive!
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