Ana’s paper describing the structure of a slightly cryptic domain from CHD4 has come out in JBC. Check out the paper here or check out the structure here. As you can see here, it looks sort of like an HMG-box domain (CHD4 is in red – HMG-box domains are in grey). HMG-box domains bind to DNA – sometimes to unusual structures… Seems like it might be involved in binding to PAR at sites of DNA damage, although that’s not set in stone at this stage…
Former Mackay lab PhD student Dorothy Wai - author of such well-known studies as "The BRD3 ET...
We finished off 2024 with one current lab member getting engaged and one former lab member also...
Perfect weather and a newly renovated lawn greeted us upon arrival at the Marrickville Croquet...
The BSc Hons students for 2024 have given all the talks, submitted all the theses and generally...
Clement (along with syn bio lab heads Dr Yu Heng Lau and Dr Constance Bailey) coached a team of...
Travelled to Seoul for the ICMRBS NMR conference - with my old Ti road bike in tow to spend 3...