We were lucky enough to have two reviews in the most recent issue of Current Opinions in Structural Biology – in the “Sequences and topology” section. Ngaio and Jacqui told the world about Mechanisms of DNA-binding specificity and functional gene regulation by transcription factors, while Joel and Steph recruited the help of Charlie Bond and Amanda Blythe to wax lyrical about the Determinants of affinity and specificity in RNA-binding proteins. To cap it off, Amanda’s image of RNA-protein hydrogel assembly was featured on the cover of the journal. A good outcome for all!