MACKAY & MATTHEWS LAB

Protein structure, function and engineering

Lab alum Kaavya smashing it in GPCR world

Jul 31, 2020

This week’s edition of Science magazine features an article on which Kaavya Krishna Kumar – PhD student with Dave Gell when he was here in our unit – is first-equal author. The paper describes the cryoEM structure of the glucagon receptor bound to a glucagon-like ligand and helps understand the mechanism by which the binding of glucagon to its GPCR receptor transmits a signal to the inside of the cell – increasing glucose production when blood glucose gets low. Great work Kaavya! [Figure taken from paper – which you can find HERE]

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