[ PDB file ] [ PubMed link ]
We have used a variety of NMR, mutagenesis and binding data to build a model of the interaction between zinc finger 5 from the neuronal transcription factor MyT1 and its cognate DNA site. The model was built using the HADDOCK data-driven docking software (from Alexandre Bonvin) and shows that the domain fits snugly into the DNA major groove, making a number of base specific hydrogen bonds and hydrophobic contacts.