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Lab receives crystallization robotics system
We recently were awarded funding to set up a robotic crystallization facility, and have purchased liquid handling, crystallization and visualization robots in order to improve our hit rate with protein crystallization. These instruments have recently arrived in the School, and promise to usher in a new era of whizz bang apparatus for Ann to play with (not to mention fast crystal screens...).
Margie wins RD Wright Fellowship
Dr Margie Sunde has just been awarded a thoroughly deserved RD Wright fellowship from the NHMRC. This five-year fellowship is very prestigious and will give Margie a great chance to consolidate her research with independent funding.
NHMRC Project Grant success
Joel and Dave, in collaboration with David Adams at the Sanger Institute in the UK, have been awarded an NHMRC Project Grant to study the structure and function of a zinc finger protein with a putative role in the regulation of alternative splicing. This project has produced some very enticing preliminary data and the funding will provide the opportunity to follow these data through.
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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