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NHMRC Project Grant success
Joel and Dave, in collaboration with David Adams at the Sanger Institute in the UK, have been awarded an NHMRC Project Grant to study the structure and function of a zinc finger protein with a putative role in the regulation of alternative splicing. This project has produced some very enticing preliminary data and the funding will provide the opportunity to follow these data through.
Joel and Jacqui win NHMRC Program Grant
Together with Merlin Crossley, Joel and Jacqui were recently awarded $2.8M in a five-year NHMRC Program Grant, to persue their work on understanding the molecular basis of gene regulation. Only a handful of these grants, which emphasize collaborations between high-performing teams of researchers, are given out each year. There was excitement all round!
Fionna and Ann win prizes at East Coast Protein Meeting
Fionna Loughlin and Ann Kwan both won prizes at the recent East Coast Protein Meeting. Held at the Opal Cove resort in Coffs Harbour, ECPM was a superbly run and very interesting meeting chaired by Philippa Stokes (a third year PhD student in the lab) and put together with her team of organizers Sharon Pursglove, Molly Clifton (both from the lab) and Kate Quinlan (Crossley lab). Fionna won an outstanding student talk award, and Ann won a prize for her first poster as a grown up.
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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