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Cover Story
Our most recent paper, a collaboration with Peter Karuso, on the solution properties of DNA-binding ruthenium complexes, made the cover of Dalton Transactions, a Royal Society of Chemistry journal.
Positions available in Mackay and Matthews Lab.
Postdoctoral and Research Assistant positions are currently available in the Mackay and Matthews labs. Download PDF advertisement for postdoc. Contact Joel or Jacqui for more information.
Joel part of largest LIEF grant for 800
A consortium headed by Gottfried Otting and Joel was recently awarded $1.53M from the ARC's large equipment grant fund (LIEF). This grant, which was the largest of its kind, will allow the purchase of an 800 MHz NMR spectrometer equipped with a cryosystem. The instrument will be situated at the Research School of Chemistry at ANU and the University of Sydney will have ~20-25% of the measurement time. This will be a tremendous boost to our capabilities, allowing the recording of full datasets in substantially reduced times, as well as greatly improving signal-to-noise over the current instrumentation.
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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