MACKAY & MATTHEWS LAB

Protein structure, function and engineering

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Mehdi and Taylor (and Camilla! – and James, and Ngaio…) graduate!

The December graduation this year was a bumper crop of PhD graduates from the Science Faculty - and also a bumper crop from Structural Biology. Mehdi Sharifi Tabar and Taylor Szyszka from Joel's lab, Ngaio Smith (in absentia) from Jacqui's lab and Camilla Faoro and James Walshe (in absentia) from Sandro's lab *all* completed the final formality before they can wear their PhD gowns to their new labs each day... Congratulations to all - it's a big achievement!

The Rock

In news of great excitement, I can announce that there is another lab matrimonial union on its way! Taylor and Rezwan have announced their engagement - in fine style while on a small weekend getaway in Mudgee. They have decided to make the most of the whole thing by having *3* weddings - so stay tuned to find out more! Congratulations to both of them!

Dave Gell’s new paper featuring old-school biochemistry

Molecular Microbiology has now published the epic piece of work spearheaded by ex-lab member Dave Gell, who is now resident at the University of Tasmania. Dave had been approached by local microbiologists who noted that some strains of Haemophilus haemolyticus inhibited the growth of Haemophilus influenzae. Dave heroically purified the factor that caused this inhibition by using culture medium - old school biochemistry! Amazingly, he found that it was a heme-binding protein - his favourite class of proteins! They could hardly have found a better person in the country to characterize this protein if they'd tried! Read all about it...

Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au

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Molecule of the Month!

Molecule of the Month!

One of our most prized structures, the GATA:FOG zinc finger complex, features in the Protein Data Bank's Molecule of the Month section for March 2007. Check it out! A couple of our recent reviews of the field (Sunde and Matthews and Gamsjaeger et al.) were also...

Mugdha wins poster prize

Mugdha wins poster prize

Mugdha Bhati won a Student Poster Prize at the recent Biomolecular Dynamics and Interactions 2007 Meeting: From Single Molecules to Complex Assemblies. With Jacqui chairing the meeting (and no she wasn't a poster judge) and Joel chairing a session, there was a very...

Fionna does it again!

Fionna does it again!

Fionna has proven that her Lorne Poster Prize this year was no fluke by winning a poster prize at the 2006 ComBio conference in Brisbane. Her poster described structural and functional details of RanBP-like zinc finger domains.