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New lab paper hits the streets
Well, this paper took quite some time to come to fruition. Biswa from Melbourne worked hard to extract a structure from some less than friendly NMR data on a protein that was gifted to us by Wayne Patrick (formerly in Otago, now in Victoria University Wellington). I'm not sure it's a gift I'd wish on anyone else, but the job is done! Well done Biswa and everyone else who lent a hand over the years...
Xavier gets to put the gown on
Xavier Reid graduated today with his BSc with first class Honours - and you can see him here accompanied by his co-supervisor, Dr Jason Low. No one will mention that Jason isn't wearing his UNSW gown... Xavier has taken the plunge to come back and start a PhD - splitting his time between digging deep into NuRD complex biochemistry and designing new high-affinity, high-specificity regulators of gene expression, using the new RaPID screening technology that has landed at USyd with the arrival of Dr Toby Passioura.
Taylor’s PhD has been formally approved!
...so feel free to congratulate her if you see her around. I'm sure there will be a celebration to follow! Well done Taylor - it's a mighty achievement.
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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