MACKAY & MATTHEWS LAB

Protein structure, function and engineering

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Showing off the coast to collaborators

We had a visit this week from David Doak - video game designer and architect of our new virtual reality app focused on allowing students to investigate the properties of polypeptides. Jane Allison - molecular dynamics aficionado from Auckland Uni who is involved in the project - popped over the ditch to join in our discussions too. So, I took the opportunity to take Jane and David on a walk from Malabar around to Coogee on the weekend - superb weather and a fantastic series of rock platforms. It's a great walk to take visitors on... And here are some of David's photos...

New lab paper hits the streets

Well, this paper took quite some time to come to fruition. Biswa from Melbourne worked hard to extract a structure from some less than friendly NMR data on a protein that was gifted to us by Wayne Patrick (formerly in Otago, now in Victoria University Wellington). I'm not sure it's a gift I'd wish on anyone else, but the job is done! Well done Biswa and everyone else who lent a hand over the years...

Xavier gets to put the gown on

Xavier Reid graduated today with his BSc with first class Honours - and you can see him here accompanied by his co-supervisor, Dr Jason Low. No one will mention that Jason isn't wearing his UNSW gown... Xavier has taken the plunge to come back and start a PhD - splitting his time between digging deep into NuRD complex biochemistry and designing new high-affinity, high-specificity regulators of gene expression, using the new RaPID screening technology that has landed at USyd with the arrival of Dr Toby Passioura.

Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au

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