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Ana’s lab baby update…
Congratulations to Ana and Callum. Ana obviously felt left out of the baby congratulations wave and so decided to have her baby a week early! Emma Silva Smits was born yesterday morning at 10.18 am and was 48 cm tall, weighing 3.06 kg (although no confidence intervals were reported for those measurements so I'm not sure about the precision). Both Emma and Ana are doing well (and are processing single particle EM data).
Welcome to new lab members – Mehdi, Jason (aka. Alex) and Taylor
We have three people joining Joel's lab in one week this week. First up, we have Mehdi Sharifitabar who hails from Iran and is starting his PhD. Taylor Szyszka (whose surname would surely win you a game of Scrabble if you could only spell it) is also a new PhD student - fresh from her degree at U Arizona. Finally Dr Jason Schmidberger wings his way to us from postdoctoral stints in Europe and will be our new resident crystallographer. In good lab tradition, we will immediately retrain him in something else, but he'll still be around to help you with your crystallography stuff. Please introduce yourself to them if you see them around.
GATA1-DNA structure published
The long-awaited structure of the double ZF of GATA1 bound to DNA - a pseudopalindromic site - has come out [Pubmed or PDF via journal] in Protein Science, thanks to the work of Lorna (including some *very* funky multi-coloured gel shifts), Krystal and Nina - and of course the inimitable David Jacques and Mitchell. Their work puts a dampener on the idea that GATA-1 might mediate DNA looping by having one ZF bind to a local site and the other to a distant site - which is just as well, otherwise Ldb1 would be left feeling redundant.
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
Amazing story from the lab down the corridor - @RezwanSidd working with Sandro Ataide and Ruth Hall in @SydneySOLES at @Sydney_Science - now they will be thrown into the gladiators' pit I suspect with the other protagonists that prowl this landscape! 🙂 Great piece of work!
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