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Jacqui invited to speak at the triennial GATA meeting in 2015
In the latest of a recent glut of international speaking invitations (Gordon Conference in the US and the Prague Spring Meeting being the most recent), Jacqui has been invited to speak at the GATA meeting, which will be held next year on the island of Kos in Greece. Nice for some!
Marylène’s paper on designer RNA-binding proteins has been accepted in Angew. Chem.
Slightly too late to allow us to celebrate with her, but a good belated going-away present nonetheless. Steph and Mitch also put in plenty of work and several other people in the lab were involved too... The full citation is: Engineering Specificity Changes on a RanBP2 Zinc Finger that binds single-stranded RNA Marylène Vandevenne, Mitchell R. O'Connell, Stephanie Helder, Nicholas E. Shepherd, Jacqueline M. Matthews, Ann H. Kwan, David J. Segal, and Joel P. Mackay* (2014) Angew. Chem. in press. Yay!
Soumya is given the nod
The official word has come through that Soumya has now qualified for her PhD degree. Graduation will no doubt follow soon, but you can practise calling her Dr Joseph in the meantime... Congratulations Soumya!
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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