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NHMRC, ARC and Cancer Council success
The lab was lucky enough to pick up a few grants in this year's annual funding bunfight. Joel was awarded an NHMRC grant with Tom Gonda and Dave Segal aimed at looking at the nucleic-acid binding properties of human transcription factors and a second one (with Nick Shepherd and Daniel Ryan) to examine the structure and interactions that make up a large chromatin remodeling complex. He was also able to renew his NHMRC Senior Research Fellowship. Jacqui was awarded an ARC grant to look at LIM homeodomain proteins and a Cancer Council NSW grant to develop inhibitors of LMO4. Hopefully these will keep us in pipette tips for 2014...
Joel advances to high school
Last week, Joel responded to a request from the science department at Ascham School in Edgecliff to visit and give a talk on protein folding - the same talk that he gave at MLC in Burwood a few months ago. Joel is talking with the teachers about additional involvement in their science curriculum over the summer break and in 2014.
Joel goes back to primary school (again).
Joel has been involved with the CSIRO's Scientists in Schools program for 5 or so years now, and recently visited his long-term partner school - Strathfield North Public School - spending 2 days with the year 5 and 6 students teaching them about the principles of electromagnetism and giving them the chance to make an electromagnetic motor themselves from basic materials. It's a great program - he would thoroughly recommend it to anyone who wanted to help raise science literacy in schools. Joel demonstrating that a currrent carrying wire has an associated magnetic field Joel creating an electromagnetic motor with several SNPS students looking...
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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