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Review from lab accepted at Nature Reviews Cancer
Hooray - Jacqui, Krystal and Soumya have just had a review accepted in Nature Reviews Cancer on the involvement of LMO proteins in cancer. Good timing with grant (and fellowship) season around the corner...!
Graduation fever
Tonight, the Sydney Protein Group had their annual Thompson Prize event, pitting PhD students from around the region against each other in 10-minute talks. We had Mitch and Morgan going head to head with students from a range of places, and in a tough context Morgan took out the prize for his talk about the crystal structure he has recently solved. Champion work Morgan (and commiserations Mitch!).
Scientists in Schools
Joel has been involved in the CSIRO Scientists in Schools program for a few years now, visiting a local primary school (Strathfield North Public School) once or twice a year to do a day of science with a bunch of the students (usually about 150 in a day in three lots). They do experiments like making electric motors, using levers and pulleys and purifying their own DNA. Recently, the school magazine discussed the visit by Joel (and Mitchell and Ann) in July: Science Week August 11-18 A feature of our science programs is our association with Dr Joel Mackay who works at Sydney University and is part of the CSIRO national program that creates and supports long-term partnerships between...
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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