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Paul insisted I put this up…
A surreptitious recording of an effort from our first jam yesterday with a 4-member ensemble - Paul on bass, Mitch on drums, Elissa Liew from Micro on keyboard (she sounds great here!) and yours truly on the tenor sax (and sounding a bit thin). [listen]. Felt great to play as a group - now we just need Flyp's trombone...
We are slowly turning Ana from the dark side…
Ana recorded her first 15N-HSQC today - and it was a ripper! Who needs those fiddly crystal things...? We will have her writing pulse programs by the end of the year...
A bumper week for papers
Jacqui has had a good couple of weeks, with 3 papers getting accepted or reviews that indicate only minor revisions are required - that backlog of papers is getting slowly but steadily cleared!
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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