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Journal cover glamour for Fionna’s structure
The journal RNA selected Fionna's crystal structure of a ZRANB2 zinc finger bound to RNA as the cover illustration for their March 2010 issue. Today the cover of RNA, tomorrow the centrefold of Cleo...
Mitch wins poster prize at Genome meeting
Eschewing the usual Lorne Protein conference this year, Mitch and a small hardcore band of transcription people headed for the Lorne Genome Conference - same location, different science! As well as the chance to hear Phil Gregory from Sangamo talk about designer zinc fingers, Mitch was able to win a prize for his poster on protein design using RanBP-type zinc fingers. Well done Mitch - will help pay for your rent increase!
Former lab member becomes a dad
Gonzalo Durante (Gonn), a visitor to the lab from Spain in 2007 (wow - time flies!) had a busy week last July, when he (a) got married, (b) defended his PhD thesis (successfully) and (c) became a father. You can see the whole family. Now, *that* was a stressful week! He is currently being a father-at-home, and planning his next career move. Maybe we will see him in Australia again?
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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