MACKAY & MATTHEWS LAB

Protein structure, function and engineering

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The 800 MHz spits out its first HSQC!

Woo-hooo - the new Bruker Avance 3 800-MHz NMR spectrometer recorded its first 15N and 13C HSQC spectra today, so we have taken our first steps in the ultra-high-field world. Exciting! The cryosystem and probe will be installed over the next 10 days or so, and then we will be rocking! Please submit purified and double/triple labelled proteins (and their binding partners, preferably!) at your leisure...

Mugdha and Ingrid blitz the Lorne Conference!

Mugdha and Ingrid both won poster prizes at the recent Lorne Conference on Protein Structure and Function for their presentations on LIM homeodomain and hydrophobin proteins, respectively. Miriam-Rose Ash and David Jacques from the crystallography side of the structural biology unit also picked up prizes too - not a bad haul overall!

Ann appointed as NMR Instrument Manager

Ann has finally given in to her desire to work in or near a workshop and been appointed as our new NMR Instrument Manager. In this, she follows in the footsteps of Dr Bill Bubb, who did an excellent job of keeping our 400 and 600-MHz instruments in tip-top condition. Ann's first job is to oversee the installation of our new 800-MHz instrument - not a bad way to kick off! I have a hunch that Ann is going to be an exceptional instrument manager...

Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?

Amazing story from the lab down the corridor - @RezwanSidd working with Sandro Ataide and Ruth Hall in @SydneySOLES at @Sydney_Science - now they will be thrown into the gladiators' pit I suspect with the other protagonists that prowl this landscape! 🙂 Great piece of work!

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