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Molecule of the Month!
One of our most prized structures, the GATA:FOG zinc finger complex, features in the Protein Data Bank's Molecule of the Month section for March 2007. Check it out! A couple of our recent reviews of the field (Sunde and Matthews and Gamsjaeger et al.) were also used to create the feature.
New postdoctoral fellow to join the lab
Dr Josep Font from Catelonia in Spain has just been awarded a Research Fellowship from the Spanish government to join the lab for two years. Josep (Pep) has worked extensively on the thermodynamics of folding of ribonuclease A, under the tutelage of Prof. Maria Vilanova at the University of Girona.
Mugdha wins poster prize
Mugdha Bhati won a Student Poster Prize at the recent Biomolecular Dynamics and Interactions 2007 Meeting: From Single Molecules to Complex Assemblies. With Jacqui chairing the meeting (and no she wasn't a poster judge) and Joel chairing a session, there was a very heavy lab influence - even if it was held in Melbourne.
Wanted: postdoc biochemist/structural biologist to work with Richard Payne, Sydney/US startup INSAMO (and me). Goal: use cyclic peptide mRNA display to design cell-permeable peptide-based protein degraders: https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Darlington-Campus/Postdoctoral-Researcher-in--Peptide-Based-Drug-Discovery_0131612-1
Email for more info: joel.mackay@sydney.edu.au
Have been off X for months but had to log in to see response to AF3. I am much less smart than the authors - but am I (and Erin) the only ones to think that the helical afros that it makes out of IDRs is totally weird? Am I missing something?
This is supercool, but it does like folding everything, even things that are probably disordered... As always, use with caution, and consult your friendly structural biologist before investing too much in low confidence predictions.
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