MACKAY & MATTHEWS LAB

Protein structure, function and engineering

N-terminal finger of GATA-1 (GNF)

N-terminal finger of GATA-1 (GNF)

[ PDB file ] [ PubMed link ] The structure of GNF consists of two distorted β-hairpins and an α-helix, with a central zinc atom (green) ligated by four cysteine residues (red). GATA-1 interacts with transcription factors from the FOG family using this N-terminal zinc...