by Joel Mackay | Sep 25, 2025 | BLOG |
The first step in the publication journey… This is the paper that describes our BET inhibitors that are super-selective – one of which seems to act by sensing differences in conformational dynamics between paralogues. It only binds to BRD2-BD1 – the...
by Joel Mackay | Aug 7, 2025 | Past Lab Members |
2025. Second year BSc student who embarked on a Dalyell (advanced) undergraduate project in Joel’s lab (Semester 2 2025) under the guidance of Erekle. She examined the biochemical properties of the BET bromodomain protein BRD3, collecting some nice data that...
by Joel Mackay | Apr 29, 2025 | BLOG |
https://mackaymatthewslab.org/wp/wp-content/uploads/2025/04/IMG_7324.mp4...
by Joel Mackay | Apr 12, 2025 | BLOG |
Former Mackay lab PhD student Dorothy Wai – author of such well-known studies as “The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators” has recently tied...
by Joel Mackay | Mar 28, 2025 | Past Lab Members |
2025. BSc Hons student who worked with Joel – bringing some molecular dynamics into the lab toolkit. Drove it himself mostly, because of Joel’s woeful lack of knowledge about AI and the nuts and bolts of setting up MD.