MACKAY & MATTHEWS LAB

Protein structure, function and engineering

Erekle Kobakhidze

Erekle Kobakhidze

2023 BSc Hons student wh worked with Joel (and Lucien and Clement) to try to unravel the mysteries of the (appallingly named) transcriptional regulator PWWP2A and its partners. Has stayed on as an RA prior to heading off overseas to expand his horizons!
Andrea Daners

Andrea Daners

PhD student working with Joel (following Hons in 2023) – focused on uncovering the mysteries of how CHD4 activity is regulated and well on her way to becoming the lab’s first genuine cryoEM practitioner.
Lucien Lambrechts

Lucien Lambrechts

PhD student working with Joel (following Hons in 2022), who impressively walked the line between chemistry and biochemistry to get native chemical ligation up and running in the lab – part of our gateway to designer nucleosomes for unravelling some of the...
Clement Luong

Clement Luong

BSc Hons student with Joel in 2022 who wasn’t deterred by the 200+ kDa of the CHD4 chromatin remodelling enzyme and has stayed on as a research assistant to look further under the hood at CHD4 activity. After dabbling in amber stop codon suppression technology,...
Lihua Yang

Lihua Yang

PhD student working with Joel to investigate the use of monobodies as reagents to modify the function of human transcription factors. Has come to the lab via China Pharmaceutical University and the University of Strathclyde in Glasgow – though he doesn’t...
Jen Suh

Jen Suh

PhD student working with Joel (after BSc Hons work in 2021) on a couple of different projects to keep her on her toes – both focused on the design of molecules to modulate gene transcription for therapeutic or agricultural outcomes.