MACKAY & MATTHEWS LAB

Protein structure, function and engineering

Marylène has been extra busy…

Not only has she been planning a wedding, but she’s been publishing senior author papers too. Here is her paper in J Mol Biol describing the combinatorial design of a nanobody that can recognized structured RNA molecules: Marylène’s paper! A nice...
New PNAS Paper for Neil, Ngaio, and Athina!

New PNAS Paper for Neil, Ngaio, and Athina!

Two papers in two days! Neil, Ngaio, and Athina just had some very exciting binding findings published in PNAS! This work includes Neil’s crazy binding kinetics equations, some gorgeous EMSA data from Ngaio, and other data from Athina, Matt, and Ann. The paper...
New JBC Paper for Dorothy and Taylor!

New JBC Paper for Dorothy and Taylor!

Hot off the presses! Dorothy and Taylor’s new ET paper just came out in JBC! This work features two solution NMR structures of the ET domain of Brd3 bound to peptides from chromatin remodelling proteins CHD4 and Brg1. This work also includes SPR data from Lorna...
Paper featured in special edition of JBC!

Paper featured in special edition of JBC!

JBC is putting out a special virtual issue with a focus on protein science in Australasia to honour the Lorne Protein conference and we received word that one of our papers is featured! “CHD4 Is a Peripheral Component of the Nucleosome Remodeling and Deacetylase...

New lab paper accepted FEBS J

Mario’s long journey to publish the carefully methodical work he and others have done on the inter-subunit interaction network within the NuRD complex has finally come to fruition as his paper is now accepted in FEBS J. We’re quite fond of the paper...